While most students will be able to skim your text, a visually impaired student will have to suffer through every word. Keeping your narrative brief serves all of your online visitors, while also limiting the need to scroll, which can cause problems for students with mobility issues.
While a sighted user can guess that an acronym is an acronym based on the capitalization, a screenreader will attempt to to voice it as a word. For example, a screenreader will interpret ILL as being ill (sickly). Avoiding acronyms not only ensures that the visually impaired user knows you are referring to Interlibrary Loan, it makes your site more usable for all visitors who may not be familiar with library terminology.
Instead of writing lengthy narrative, use lists to keep your writing concise & to allow the user to skim for key points.
Instead of using the visual editor to enlarge the font-size of text that you want to "stand out" (for example, when you are changing ideas or categories of text), use "Headings" (h1, h2, h3 etc) to increase the size. In addition to making the font larger, screen readers and keyboard commands will allow visitors to "skip ahead" to the relevant content area.
Regardless of your personal preferences, the font styles & colors that you use should be uniform with your library's other guides. A few words of cautionary advice: